ABSTRACT
Summary@#Flagellate erythema is characterized by “whiplike’’ linear streaks, usually following bleomycin chemotherapy or is associated with consumption of shiitake mushrooms, dermatomyositis, adult onset still disease as well as human immunodeficiency disease. Here, we describe a case of bleomycin-induced flagellate erythema in a patient with Hodgkin lymphoma.
ABSTRACT
La dermatitis por hongos Shiitake ocurre en un pequeño porcentaje de casos luego de la ingesta de este hongo en forma cruda o semi-cruda. Se manifiesta usualmente como una dermatosis flagelada localizada principalmente en la espalda y en forma más ocasional con otro tipo de lesiones incluyendo la urticaria, petequias y una dermatitis de contacto entre otras. Este estudio describe un paciente sano de 46 años con dos tipos diferentes de reacciones al hongo, espaciadas en el tiempo. Primero está la típica dermatosis flagelada luego de la ingesta del hongo Shiitake y un tiempo después luego de que se había mejorado completamente, un segundo rash en la forma de dermatitis de contacto con descamación y prurito de las manos y dedos luego de la manipulación del hongo. Según nuestro conocimiento, este es el primer caso con dos diferentes formas de presentación clínica de reacción alérgica al hongo Shiitake en el mismo paciente
Shiitake fungal dermatitis occurs in a small percentage of cases after ingestion of this raw or semi-raw mushroom. It usually manifests as flagellated dermatosis located mainly on the back and more rarely with other types of lesions, including urticaria, petechiae, and contact dermatitis, among others. This study described a healthy 46-year-old male patient who presented two different forms of reaction to mushrooms, spaced over time. First is the typical form of flagellated dermatosis after the Shiitake mushrooms ingestion, and shortly after, when fully recovered, with a second rash in the form of contact dermatitis with desquamation and itching of hands and fingers after the mushroom manipulation. To the best of our knowledge, this is the first case reported with two different cutaneous clinical forms of allergic reaction to Shiitake mushrooms in the same patient.
Subject(s)
Humans , Male , Middle Aged , Shiitake Mushrooms , Dermatitis, Contact/diagnosis , Dermatomycoses , Urticaria , Epidemiology, Descriptive , Dermatitis, Contact/drug therapyABSTRACT
El eritema flagelado es una erupción cutánea poco frecuente con múltiples causas, dentro de las cuales se encuentra la ingesta de hongos shiitake crudos o semicrudos. Se postula que es secundario a una reacción de hipersensibilidad Th-1 producida por el lentinan, un polisacárido termolábil de la pared celular del hongo. En años recientes ha aumentado su incidencia en el mundo occidental debido a la creciente popularidad de la comida asiática, en la que los hongos shiitake son un ingrediente muy utilizado. El cuadro clínico se caracteriza por la aparición de lesiones eritematosas lineales pruriginosas principalmente en tronco y extremidades, de curso autolimitado. El diagnóstico es principalmente clínico, basado en el antecedente de ingesta reciente de hongos shiitake y el rash característico y el tratamiento es sintomático con antihistamínicos y corticoides tópicos u orales. A continuación, presentamos un caso de eritema flagelado en una mujer joven, secundario a ingesta de hongos shiitake, que se resolvió completamente en 2 semanas.
Flagellate erythema is a rare skin eruption with many causes, including the ingestion of raw or undercooked shiitake mushrooms. It is thought to be a Th-1 hypersensitivity reaction produced by lentinan, a thermolabile polysaccharide found in the cell wall of the mushroom. In recent years, there has been an increase in the number of cases due to the growing popularity of Asian cuisine, in which shiitake mushrooms are a central ingredient. The clinical presentation is characterized by the appearance of linear, erythematous, pruritic lesions mostly on the trunk and extremities, of self-limited course. Diagnosis is mainly clinical, based on the history of recent shiitake mushroom ingestion and the characteristic rash, and treatment is symptomatic, with antihistamines and topical or systemic steroids. In this report, we present a case of flagellate erythema in a young woman, that appeared after the ingestion of shiitake mushrooms, and resolved completely after 2 weeks.
Subject(s)
Humans , Female , Adult , Mushroom Poisoning/diagnosis , Mushroom Poisoning/etiology , Shiitake Mushrooms , Erythema/diagnosis , Erythema/etiology , Mushroom Poisoning/drug therapy , Erythema/drug therapy , Histamine Antagonists/therapeutic useABSTRACT
Shiitake (Lentinus edodes) is the second most consumed mushroom in the world. It has long been known in Asian medicine for its anticarcinogenic, antihypertensive and serum cholesterol level reduction properties. Nevertheless, the consumption of raw or not well-cooked mushrooms may cause skin eruptions which usually occur 24 to 48 hours after ingestion and are characterized by linearly arranged pruritic erythematous papules and plaques. We present a 36-year-old patient that developed typical symptoms 24 hours after consumption of shiitake mushrooms and summarize therapeutic options and particularities of this disease.
Shiitake (Lentinus edodes) é o segundo tipo de cogumelo mais consumido no mundo. Suas propriedades terapêuticas antitumorais, anti-hipertensivas e redutoras dos níveis elevados de colesterol são há muito conhecidas pela população asiática. Após ingestão desse cogumelo, cru ou malcozido, podem desenvolver-se lesões eritematosas lineares, pruriginosas, que surgem após 24 ou 48 horas em todo o corpo. Apresentamos um paciente de 36 anos com anamnese e clínica típicos, e comentamos as alternativas terapêuticas e nuances dessa dermatose.
Subject(s)
Adult , Humans , Male , Dermatitis/etiology , Food Hypersensitivity/etiology , Shiitake Mushrooms , Dermatitis/diagnosis , Food Hypersensitivity/diagnosisABSTRACT
Cochlosoma sp. infection was identified in a single case among 60 stunted diarrheic native turkey poults, Meleagris galopavo. A large number of the flagellated parasites was found free or within the intervillous spaces of the jejunum, ileum and cecum. Moderate enteritis was associated with the parasites. In TEM studies of the parasagittal sections of the parasite, a prominent ventral sucker like disc and flagella emerging from an opening on the ventrodorsal surface of the pyriform uninuclear parasite were found. The morphological characteristics of this protozoan match with those described for Cochlosoma anatis. The parasite could be considered as an intestinal pathogenic protozoan causing stunting and diarrhea in turkeys in Iran.
Subject(s)
Animals , Cecum/parasitology , Enteritis/diagnosis , Ileum/parasitology , Iran , Jejunum/parasitology , Organelles/ultrastructure , Poultry Diseases/diagnosis , Protozoan Infections, Animal/diagnosis , Trichomonadida/cytology , TurkeysABSTRACT
Megaselia scalaris (Diptera: Phoridae) is one of the medically important insects. Maggots from a urine sample of a 5-year-old Saudi girl were examined microscopically for identification. These maggots were cultured to become adult flies. Larvae and adults were identified using standard keys. Protozoan flagellates were obtained from the gut of the larvae. This is the first report of M. scalaris as a causative agent of urinary human myiasis in Saudi Arabia.
Subject(s)
Animals , Child, Preschool , Female , Humans , Diptera/parasitology , Larva/parasitology , Myiasis/parasitology , Eukaryota/isolation & purification , Saudi ArabiaABSTRACT
Megaselia scalaris (Diptera: Phoridae) is one of the medically important insects. Maggots from a urine sample of a 5-year-old Saudi girl were examined microscopically for identification. These maggots were cultured to become adult flies. Larvae and adults were identified using standard keys. Protozoan flagellates were obtained from the gut of the larvae. This is the first report of M. scalaris as a causative agent of urinary human myiasis in Saudi Arabia.
Subject(s)
Animals , Child, Preschool , Female , Humans , Diptera/parasitology , Larva/parasitology , Myiasis/parasitology , Eukaryota/isolation & purification , Saudi ArabiaABSTRACT
Spatial and temporal variability of the phytoplankton community in the tropical coastal Imboassica lagoon, an environment naturally isolated from the ocean by a narrow sandbar, was analysed every two weeks for 19 months by sampling three sites. During this study, the lagoon received direct input of marine water three times, resulting in remarkable salinity, nutrient concentrations and phytoplankton biomass variations in both temporal and spatial aspects. The phytoplankton biomass presented relatively low values ranging, on average, from 0.54 mg.L-1 in the station closest to the sea (station 1) to 1.34 mg.L-1 in the station close to a macrophyte bank (station 3). Diatoms and cryptomonads dominated in stations 1 and 2 (located relatively close to station 1, yet receiving the runoff of domestic sewage), and euglenoids, cryptomonads and dinoflagellates at station 3. Stations 1 and 2 usually presented the same dominant species but station 2 presented a higher phytoplankton biomass. On the other hand, station 3 showed more similar results concerning phytoplankton biomass with station 2, however the dominant species were usually different. The high fluctuations of salinity and the reduced nutrient availability are pointed out as the main factors structuring the dynamics of the phytoplankton community at the Imboassica lagoon.
Variações espaciais e temporais da comunidade fitoplanctônica da lagoa Imboassica, um ambiente naturalmente isolado do oceano por uma estreita barra de areia, foram analisadas com base em coletas quinzenais, realizadas em três estações, durante 19 meses. Durante este estudo, a barra de areia foi rompida três vezes, resultando em acentuadas variações temporais e espaciais na salinidade, na concentração de nutrientes e na biomassa fitoplanctônica. Esta apresentou valores relativamente baixos, variando de 0,54 mg.L-1 na estação mais próxima ao mar (estação 1) a 1,34 mg.L-1 na estação próxima a um banco de macrófitas (estação 3). Diatomáceas e criptofíceas dominaram nas estações 1 e 2 (esta última localizada, relativamente próxima à estação 1, porém recebendo aporte de esgotos domésticos), e euglenofíceas, criptofíceas e dinofíceas na estação 3. As estações 1 e 2 apresentaram, de modo geral, as mesmas espécies dominantes, diferindo neste aspecto da estação 3, no entanto, esta diferiu significantemente apenas da estação 1, em termos de biomassa fitoplanctônica. As elevadas flutuações na salinidade e a reduzida disponibilidade de nutrientes são apontadas como os principais fatores estruturadores da dinâmica da comunidade fitoplanctônica na lagoa Imboassica.
Subject(s)
Animals , Phytoplankton/classification , Brazil , Population Density , Population Dynamics , Seasons , SeawaterABSTRACT
Bleomycin is an antitumoral antibiotic derived from Streptomyces verticillus in 1965. The drug has been used with a varying success in the treatment of squamous cell carcinomas and malignant lymphomas. The cutaneous toxicities of bleomycin include hyperpigmentation, sclerosis, gangrene, nail changes and erythema. Linear streaks appear to be a characteristic eruption induced by bleomycin. We report three cases of flagellate pigmentation from intravenous bleomycin. Three patients were suffering from uterine cervical carcinomas and were treated with chemotherapy with a VBP (vincristine, bleomycin, cisplatire) regimen. During or after their courses of chemotherapy, dark brownish skin lesions developed on the body surface of these patients. A Light microscopic study of each specimen showed increased pigmentation of the basal layer and an electron microscopic study showed a slightly increased number of melanosomes in keratinocytes.